Modelling tick bite risk by combining random forests and count data regression models.

The socio-economic and demographic changes that occurred over the past 50 years have dramatically expanded urban areas around the globe, thus bringing urban settlers in closer contact with nature. 

Ticks have trespassed the limits of forests and grasslands to start inhabiting green spaces within metropolitan areas. Hence, the transmission of pathogens causing tick–bornediseases is an important threat to public health. Using volunteered tick bite reports collected by two Dutch initiatives, here we present a method to model tick bite risk using human exposure and tick hazard predictors.

Our method represents a step forward in risk modelling, since we combine a well-known ensemble learning method, Random Forest, with four count data models of the (zero-inflated) Poisson family.

This combination allows us to better model the disproportions inherent in the volunteered tick bite reports. Unlike canonical machine learning models, our method can capture the overdispersion or zero-inflation inherent in data, thus yielding tick bite risk predictions that resemble the original signal captured by volunteers. Mapping model predictions enables a visual inspection of the spatial patterns of tick bite risk in the Netherlands.

The Veluwe national park and the Utrechtse Heuvelrug forest, which are large forest-urban interfaces with several cities, are areas with high tick bite risk. This is expected, since these are popular places for recreation and tick activity is high in forests. However, our model can also predict high risk in less-intensively visited recreational areas, such as the patchy forests in the northeast of the country, the natural areas along the coastline, or some of the Frisian Islands. Our model could help public health specialists to design mitigation strategies for tick–bornediseases, and to target risky areas with awareness and prevention campaigns.

hsa-miR-643 miRNA Antagomir
MNH03298 2 x 5.0 nmol
EUR 329

Anti-UNC5B (aa629-643) antibody
STJ72651 100 µg
EUR 359

Zinc Finger Protein 643 (ZNF643) Antibody
abx036524-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Zinc Finger Protein 643 (ZNF643) Antibody
abx030432-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Zinc Finger Protein 643 (ZNF643) Antibody
abx030432-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Recombinant (HEK) Hemagglutinin Influenza A Virus H3N2 Wyoming 3/03
RP-643 2 ug
EUR 164

Polyclonal UNC5B (aa629-643) Antibody (internal region)
APR13924G 0.1 mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human UNC5B (aa629-643) (internal region). This antibody is tested and proven to work in the following applications:

Recombinant ErbB3 Protein (Ser 20-Thr 643)
VAng-1508Lsx-200g 200 µg
EUR 3487
Description: Biotinylated Human ErbB3 (Her3) is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Recombinant ErbB3 Protein (Ser 20-Thr 643)
VAng-1508Lsx-25g 25 µg
EUR 848
Description: Biotinylated Human ErbB3 (Her3) is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Human Zinc finger protein 643, ZNF643 ELISA KIT
ELI-40775h 96 Tests
EUR 824

Human pre-microRNA Expression Construct Lenti-miR-643
PMIRH643PA-1 Bacterial Streak
EUR 684
  • Category: MicroRNA Tools

Human ErbB3 Protein (Ser 20-Thr 643) [His]
VAng-1512Lsx-100g 100 µg
EUR 765
Description: Human ErbB3 (Her3), His tag, is expressed in HEK 293 cells. (Uniprot ID: P21860-1)

Human ErbB3 Protein (Ser 20-Thr 643) [His]
VAng-1512Lsx-1mg 1 mg
EUR 4009
Description: Human ErbB3 (Her3), His tag, is expressed in HEK 293 cells. (Uniprot ID: P21860-1)

Recombinant ErbB3 Protein (Ser 20-Thr 643) [Strep]
VAng-1513Lsx-1mg 1 mg
EUR 6374
Description: Human ErbB3 (Her3), Strep tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Recombinant ErbB3 Protein (Ser 20-Thr 643) [Strep]
VAng-1513Lsx-250g 250 µg
EUR 2470
Description: Human ErbB3 (Her3), Strep tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Recombinant ErbB3 Protein (Ser 20-Thr 643) [Strep]
VAng-1513Lsx-25g 25 µg
EUR 765
Description: Human ErbB3 (Her3), Strep tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Recombinant Clostridium Perfringens thrS Protein (aa 1-643)
VAng-Lsx00890-inquire inquire Ask for price
Description: Clostridium Perfringens Threonine--tRNA ligase, recombinant protein.

Recombinant Pasteurella Multocida thrS Protein (aa 1-643)
VAng-Cr7401-inquire inquire Ask for price
Description: Pasteurella Multocida (strain Pm70) Threonine--tRNA ligase (thrS), recombinant protein.

Recombinant Haemophilus Influenzae thrS Protein (aa 1-643)
VAng-Lsx03900-inquire inquire Ask for price
Description: Haemophilus Influenzae (strain PittEE) Threonine--tRNA ligase, recombinant protein.

Recombinant Human ERBB3 Protein (aa 1-643) [Fc]
VAng-Cr3988-100g 100 µg
EUR 1687
Description: Recombinant Human ERBB3 Protein (Met 1-Thr 643) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 95.4 kDa. (Accession ID: NP_001973.2)

Recombinant Human ERBB3 Protein (aa 1-643) [Fc]
VAng-Cr3988-50g 50 µg
EUR 1027
Description: Recombinant Human ERBB3 Protein (Met 1-Thr 643) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 95.4 kDa. (Accession ID: NP_001973.2)

Recombinant Rhesus ERBB3 Protein (aa 1-643) [Fc]
VAng-Cr3989-100g 100 µg
EUR 1687
Description: Recombinant Rhesus ERBB3 Protein (Met 1-Thr 643) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 95.7 kDa. (Accession ID: XP_001113953.2)

Recombinant Rhesus ERBB3 Protein (aa 1-643) [Fc]
VAng-Cr3989-50g 50 µg
EUR 1027
Description: Recombinant Rhesus ERBB3 Protein (Met 1-Thr 643) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 95.7 kDa. (Accession ID: XP_001113953.2)

Recombinant Mycobacterium Tuberculosis aftA Protein (aa 466-643)
VAng-Yyj0006-1mgEcoli 1 mg (E. coli)
EUR 3689
Description: Mycobacterium Tuberculosis Arabinofuranosyltransferase AftA (aftA), recombinant protein.

Recombinant Plasmodium Falciparum PF11_0090 Protein (aa 1-643)
VAng-Wyb6639-inquire inquire Ask for price
Description: Plasmodium Falciparum (isolate 3D7) Pescadillo homolog, partial, recombinant protein.

Recombinant Caenorhabditis Elegans B0464.6 Protein (aa 1-643)
VAng-Ly3060-inquire inquire Ask for price
Description: Caenorhabditis Elegans uncharacterized protein B0464.6 (B0464.6), partial, recombination protein.

Recombinant Caenorhabditis Elegans C06E1.9 Protein (aa 1-643)
VAng-Ly3118-inquire inquire Ask for price
Description: Caenorhabditis Elegans uncharacterized protein C06E1.9 (C06E1.9), partial, recombination protein.

Recombinant Mycobacterium Leprae dxs Protein (aa 1-643)
VAng-Yyj1920-inquire inquire Ask for price
Description: Mycobacterium Leprae 1-deoxy-D-xylulose-5-phosphate synthase (dxs), recombinant protein.

Recombinant Klebsiella Pneumoniae deaD Protein (aa 1-643)
VAng-Cr4749-inquire inquire Ask for price
Description: Klebsiella Pneumoniae (strain 342) Cold-shock DEAD box protein A (deaD), recombinant protein.

Recombinant Clostridium Botulinum CLD_0573 Protein (aa 1-643)
VAng-Lsx8042-inquire inquire Ask for price
Description: Clostridium Botulinum (strain Okra / Type B1) UPF0313 protein CLD_0573, recombinant protein.

Recombinant Mycoplasma Capricolum gyrB Protein (aa 1-643)
VAng-Lsx06200-inquire inquire Ask for price
Description: Mycoplasma Capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) DNA gyrase subunit B, recombinant protein.

Recombinant Mycobacterium Bovis aftA Protein (aa 1-643)
VAng-Yyj3213-inquire inquire Ask for price
Description: Mycobacterium Bovis Arabinofuranosyltransferase AftA (aftA), recombinant protein.

Rabbit Anti-Human STAT6 Polyclonal Antibody, aa.643-647
CPB-963RH 100 ul
EUR 460

Rabbit Anti-Human PRKCD (aa 643-647) Polyclonal Antibody
CPB-1170RH 100 ul
EUR 460

Human ErbB3 Protein (Ser 20-Thr 643) [Fc] (NP_001973.2)
VAng-1510Lsx-1mg 1 mg
EUR 4009
Description: Human ErbB3 (Her3), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Human ErbB3 Protein (Ser 20-Thr 643) [Fc] (NP_001973.2)
VAng-1510Lsx-200g 200 µg
EUR 985
Description: Human ErbB3 (Her3), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001973.2)

Human ErbB3 Protein (Ser 20-Thr 643) [Fc] (P21860-1)
VAng-1509Lsx-100g 100 µg
EUR 875
Description: Human ErbB3 (Her3), Mouse IgG2a Fc Tag, is expressed in HEK 293 cells. (Uniprot ID: P21860-1)

Human ErbB3 Protein (Ser 20-Thr 643) [Fc] (P21860-1)
VAng-1509Lsx-1mg 1 mg
EUR 5494
Description: Human ErbB3 (Her3), Mouse IgG2a Fc Tag, is expressed in HEK 293 cells. (Uniprot ID: P21860-1)

FITC-Labeled Human ErbB3 Protein (Ser 20-Thr 643) [His]
VAng-1511Lsx-200g 200 µg
EUR 5219
Description: FITC-Labeled Human ErbB3 (Her3), His Tag, is expressed in HEK 293 cells. (Uniprot ID: P21860-1)

FITC-Labeled Human ErbB3 Protein (Ser 20-Thr 643) [His]
VAng-1511Lsx-25g 25 µg
EUR 848
Description: FITC-Labeled Human ErbB3 (Her3), His Tag, is expressed in HEK 293 cells. (Uniprot ID: P21860-1)

Recombinant Mycobacterium Leprae dxs Protein (aa 1-643) (strain Br4923)
VAng-Yyj1921-inquire inquire Ask for price
Description: Mycobacterium Leprae (strain Br4923) 1-deoxy-D-xylulose-5-phosphate synthase (dxs), recombinant protein.

Anti-ERBB2 (trastuzumab)-Aminocaproyl-MMAF ADC
ADC-W-643 1mg Ask for price
Description: This ADC product is comprised of an anti-ERBB2 antibody (trastuzumab) conjugated via a Aminocaproyl linker to MMAF

Anti-Hu CD361 Purified
11-643-C025 0.025 mg
EUR 99

Anti-Hu CD361 Purified
11-643-C100 0.1 mg
EUR 158

Anti-Hu CD361 APC
1A-643-T100 100 tests
EUR 240

Anti-Hu CD361 PE
1P-643-T025 25 tests
EUR 140

Anti-Hu CD361 PE
1P-643-T100 100 tests
EUR 240

Recombinant Clostridium Perfringens thrS Protein (aa 1-643) (strain SM101 / Type A)
VAng-Lsx01214-inquire inquire Ask for price
Description: Clostridium Perfringens (strain SM101 / Type A) Threonine--tRNA ligase, recombinant protein.

Recombinant Clostridium Perfringens thrS Protein (aa 1-643) (strain ATCC 13124 / NCTC 8237 / Type A)
VAng-Lsx01215-inquire inquire Ask for price
Description: Clostridium Perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Threonine--tRNA ligase, recombinant protein.

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