Dynamic rodent behavioral response to predation risk: implications for disease ecology.

Prey modify their behavior in response to variation in predation risk, and such modifications can affect trophic processes such as disease transmission. However, variation in predation risk is complex, arising from direct risk from the predator itself and indirect risk due to the environment.

Moreover, direct risk typically stems from multiple predators and varies over timescales (e.g., a predator nearby vs. its seasonal activities). We implemented a field-based experiment to disentangle these sources of risk and relate them to antipredator behavior in rodents. We modeled rodent occurrence and activity as a function of short- and long-term risk from a primary predator, red foxes (Vulpes vulpes), long-term risk from a second predator, coyotes (Canis latrans), and environmental variables.

We found that long-term red fox activity strongly reduced rodent occurrence and that cues of nearby red fox presence decreased rodent activity by > 50%. In addition, this activity reduction was dynamic in that varied according to the background level of long-term red fox activity. Importantly, rodents did not respond to environmental variables (moonlight, temperature, and habitat) or long-term coyote activity.

These results bear upon recent work that suggests predators can alter tickbornedisease dynamics via induced antipredator behavior of rodents, which are hosts for pathogens and ticks. Specifically, our study corroborates the hypothesis that red foxes act as important proximal agents in regulating tickbornediseases by reducing rodent activity. More generally, this study highlights the need to consider the dynamic nature of prey antipredator response across landscapes with variable long-term predation risk.

hsa-miR-651-3p Primers

MPH03431 150 ul / 10 uM
EUR 121

hsa-miR-651-5p Primers

MPH03436 150 ul / 10 uM
EUR 121

hsa-miR-651-3p miRNA Inhibitor

MIH03340 2 x 5.0 nmol
EUR 176

hsa-miR-651-5p miRNA Inhibitor

MIH03345 2 x 5.0 nmol
EUR 176

hsa-miR-651-3p miRNA Antagomir

MNH03340 2 x 5.0 nmol
EUR 329

hsa-miR-651-5p miRNA Antagomir

MNH03345 2 x 5.0 nmol
EUR 329

Recombinant (E.Coli) Measles Virus Large Polymerase (58-149)

RP-651 100 ug
EUR 286

ROR 1 Recombinant Protein

96-651 0.1 mg
EUR 626.75
Description: Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.

DKK-2 Recombinant Protein

40-651 2 ug
EUR 259.25
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions.

MGAT2 Recombinant Protein

91-651 0.05 mg
EUR 710.75
Description: Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

Prolactin receptor Recombinant Protein

92-651 0.05 mg
EUR 401
Description: The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues. PRLRs are expressed in normal and neoplastic human breast tissue, and in most breast cancer cells. PRLR contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region required for the activation of the Jak2–Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes. PRLRs have also been observed in ovarian follicular cells of mice, pigs, sheep, deer, and humans, as well as in luteal tissue in cow and horse ovaries. Furthermore, PRLR knockout mice exhibit failure of embryonic implantation, reduced number of mature oocytes, and low fertilization rates. Knockout females also display a reduced number of primary follicles.

Recombinant ErbB4 Protein (Gln 26-Pro 651) [Fc]

VAng-1514Lsx-100g 100 µg
EUR 765
Description: Human ErbB4 (Her4), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001036064.1)

Recombinant ErbB4 Protein (Gln 26-Pro 651) [Fc]

VAng-1514Lsx-1mg 1 mg
EUR 4009
Description: Human ErbB4 (Her4), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001036064.1)

Recombinant ErbB4 Protein (Gln 26-Pro 651) [His]

VAng-1515Lsx-100g 100 µg
EUR 820
Description: Human ErbB4 (Her4), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_005226.1)

Recombinant ErbB4 Protein (Gln 26-Pro 651) [His]

VAng-1515Lsx-1mg 1 mg
EUR 4724
Description: Human ErbB4 (Her4), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_005226.1)

Recombinant Mycobacterium Leprae priA Protein (aa 1-651)

VAng-Yyj2280-inquire inquire Ask for price
Description: Mycobacterium Leprae Putative primosomal protein N'(priA), recombinant protein.

Recombinant Yersinia Enterocolitica Invasin Protein (aa 651-835)

VAng-Wyb1574-10g 10 µg
EUR 600
Description: Yersinia Enterocolitica Invasin, recombinant protein.

Recombinant Yersinia Enterocolitica rppH Protein (aa 1-651)

VAng-Wyb1796-1mgEcoli 1 mg (E. coli)
EUR 3525
Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) RNA pyrophosphohydrolase, recombinant protein.

Recombinant Yersinia Enterocolitica rppH Protein (aa 1-651)

VAng-Wyb1796-500gEcoli 500 µg (E. coli)
EUR 2548
Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) RNA pyrophosphohydrolase, recombinant protein.

Recombinant Yersinia Enterocolitica rppH Protein (aa 1-651)

VAng-Wyb1796-50gEcoli 50 µg (E. coli)
EUR 1630
Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) RNA pyrophosphohydrolase, recombinant protein.

Recombinant Echinococcus Granulosus GRP78 Protein (aa 21-651)

VAng-Ly4006-inquire inquire Ask for price
Description: Echinococcus Granulosus 78 kDa glucose-regulated protein (GRP78), partial, recombination protein.

Recombinant Brucella Abortus kup Protein (aa 1-651)

VAng-Lsx5331-inquire inquire Ask for price
Description: Brucella Abortus (strain 2308) Probable potassium transport system protein kup, recombinant protein.

Recombinant Brucella Ovis acsA Protein (aa 1-651)

VAng-Lsx5528-inquire inquire Ask for price
Description: Brucella Ovis (strain ATCC 25840 / 63/290 / NCTC 10512) Acetyl-coenzyme A synthetase, recombinant protein.

Recombinant Brucella Suis acsA Protein (aa 1-651)

VAng-Lsx5557-inquire inquire Ask for price
Description: Brucella Suis (strain ATCC 23445 / NCTC 10510) Acetyl-coenzyme A synthetase, recombinant protein.

Recombinant Haemophilus Influenzae rnfC Protein (aa 1-651)

VAng-Lsx03681-inquire inquire Ask for price
Description: Haemophilus Influenzae (strain PittEE) Electron transport complex protein RnfC, recombinant protein.

Recombinant Human ErbB4 Protein (aa 1-651) [His]

VAng-Cr3992-100g 100 µg
EUR 1687
Description: Recombinant Human ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 97.5 kDa. (Accession ID: NP_001036064.1)

Recombinant Human ErbB4 Protein (aa 1-651) [His]

VAng-Cr3992-50g 50 µg
EUR 1027
Description: Recombinant Human ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 97.5 kDa. (Accession ID: NP_001036064.1)

Recombinant Rat ErbB4 Protein (aa 1-651) [His]

VAng-Cr3993-100g 100 µg
EUR 1687
Description: Recombinant Rat ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.3 kDa. (Accession ID: AAQ77349.1)

Recombinant Rat ErbB4 Protein (aa 1-651) [His]

VAng-Cr3993-50g 50 µg
EUR 1027
Description: Recombinant Rat ErbB4 Protein (Met 1-Pro 651) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 71.3 kDa. (Accession ID: AAQ77349.1)

Recombinant Rat ErbB4 Protein (aa 1-651) [Fc]

VAng-Cr3996-100g 100 µg
EUR 1687
Description: Recombinant Rat ErbB4 Protein (Met1-Pro651) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.9 kDa. (Accession ID: AAQ77349.1)

Recombinant Rat ErbB4 Protein (aa 1-651) [Fc]

VAng-Cr3996-50g 50 µg
EUR 1027
Description: Recombinant Rat ErbB4 Protein (Met1-Pro651) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 96.9 kDa. (Accession ID: AAQ77349.1)

Recombinant Mycobacterium Gilvum htpG Protein (aa 1-651)

VAng-Yyj3912-inquire inquire Ask for price
Description: Mycobacterium Gilvum (strain PYR-GCK) (Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)) Chaperone protein htpG (htpG), recombinant protein.

Recombinant Mycobacterium Vanbaalenii htpG Protein (aa 1-651)

VAng-Yyj5071-inquire inquire Ask for price
Description: Mycobacterium Vanbaalenii (strain DSM 7251 / PYR-1) Chaperone protein htpG (htpG), recombinant protein.

Human pre-microRNA Expression Construct Lenti-miR-651

PMIRH651PA-1 Bacterial Streak
EUR 684

Recombinant Yersinia Enterocolitica aaeB Protein (aa 1-651) (strain 8081)

VAng-Cr1693-1mgEcoli 1 mg (E. coli)
EUR 6672
Description: Yersinia Enterocolitica serotype O:8 / biotype 1B (strain 8081) p-hydroxybenzoic acid efflux pump subunit AaeB (aaeB), recombinant protein.

Anti-ACVR2B (Bimagrumab)-SPDB-DM4 ADC

ADC-W-651 1mg Ask for price
Description: This ADC product is comprised of an anti-ACVR2B monoclonal antibody conjugated via a SPDB linker to DM4

Anti-Notch1 APC

1A-651-C025 0.025 mg
EUR 122

Anti-Notch1 APC

1A-651-C100 0.1 mg
EUR 204

Anti-Notch1 PE

1P-651-C025 0.025 mg
EUR 122

Anti-Notch1 PE

1P-651-C100 0.1 mg
EUR 204

Anti-Notch1 Purified

11-651-C025 0.025 mg
EUR 99

Anti-Notch1 Purified

11-651-C100 0.1 mg
EUR 158

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